A note on the development of the anterior chamber angle.

day completed synaptic organs were abundant in the outer plexiform layer. Development of the inner synapses was found to be considerably slower than that of the outer ones. The loose cell processes in the inner plexiform layer began to form certain cellular junctions around the fifth day. However, the synaptic bars and vesicles were first seen on the eighth day. On the tenth day, the inner plexiform layer became more compact and the intercellular spaces were filled with Muller's cells. The synaptic organs became apparent and abundant on the twelfth day (Fig. 10). The development of the lamellar membranes and the synaptic organs progressed equally at an extremely rapid speed. As the differentiation was so fast, marked differences were often observed between animals killed in an interval of 6 hours during the period of 4 to 7 days. On the eighth day, both the lamellar membranes and the outer synaptic organs were abundantly formed. However, the electroretinographic response was not recorded up to this developmental stage. After the rough completion of the development of the lamellar membrane and outer synaptic organs, inner synapses were formed. At this time the electroretinogram became positive. The earliest response was recorded in some animals on the eleventh day. The magnitude of the electroretinographic response increased markedly by the hour during the twelfth to fourteenth days; hence, the response was about the same as that of the normal adult rat (Fig. 11).